Glassifier Peptide Skin Treatment
Minimally Invasive Peptide Skin Treatment with Dr. Marie Hayag
How Does Glassifier’s Spicule Technology Work?
Glassifier uses patented spicule technology and a proprietary topical massage protocol to precisely deliver GHK peptide into the skin.
ALTUM® Peptides penetrate the skin barrier and reach the epidermal layer. There, glutathione in your skin breaks the chemical bond between the peptide and its carrier. The released peptides stimulate fibroblasts, which stimulates collagen production and boosts skin regeneration.
Each session takes approximately 20 minutes, and Dr. Hayag plans your course of 3–5 sessions, spaced 2–4 weeks apart, around your skin’s needs.
How it Works
- Delivers GHK peptide with patented spicule technology
- Peptides reach the epidermal layer
- Glutathione in the skin releases the peptide from its carrier
- Released peptides stimulate fibroblasts
- Stimulates collagen production to boost skin regeneration
Professional Physician-Led Glassifier Treatments
GLASS-LIKE RADIANCE
Designed to visibly improve fine lines, skin texture, and pigmentation for a glass-like radiance.
PATENTED SPICULE TECHNOLOGY
Precisely delivers GHK peptide into the skin through a proprietary topical massage protocol.
ABOUT 20 MINUTES, MINIMAL DOWNTIME
A minimally invasive treatment that takes approximately 20 minutes per session.
PERSONALIZED TREATMENT COURSE
Glassifier is recommended as a course of 3–5 sessions spaced 2–4 weeks apart. Dr. Hayag tailors your plan to your skin and goals.
What Is Glassifier Peptide Skin Treatment?
Glassifier is a minimally invasive peptide skin treatment powered by patented spicule technology. It precisely delivers GHK peptide into the skin to visibly improve fine lines, skin texture, and pigmentation, helping you achieve a glass-like radiance.
Glassifier is performed through a proprietary topical massage protocol in approximately 20 minutes, with minimal downtime. It is recommended as a course of 3–5 sessions spaced 2–4 weeks apart.
Who Glassifier May Help
Glassifier may be appropriate for adults noticing:
- Uneven skin tone or sunspots
- Post-inflammatory hyperpigmentation (PIH)
- Static wrinkles or fine lines
- Early wrinkles around the mouth and eyes
- Surface-level texture aging
- Enlarged pores
- Rough or uneven skin surface
- Dullness or lack of radiance



Before and After Glassifier.
Individual results vary.




Benefits & Why Patients Choose Glassifier



- Minimally invasive peptide skin treatment
- About 20 minutes per session
- Minimal downtime
- Visibly improves fine lines and wrinkles
- Targets uneven tone, sunspots, and PIH
- Refines rough texture and enlarged pores
- Stimulates collagen production
- Boosts skin regeneration
- Helps you achieve a glass-like radiance



Refined Dermatology, Aesthetic, And Regenerative Care
- Board Certified Expertise
- Customized Care Plans
- Advanced Treatment Options
- Trusted Clinical Excellence
- Upper East Side, New York City
Excellent rating
Based on 110 reviews![]()
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Trustindex verifies that the original source of the review is Google.
Dr. Hayag has been my excellent dermatologist for more than 20 years! I won’t reveal my secrets but I will recommend her highly!
Phyllis LeeTrustindex verifies that the original source of the review is Google.
I had an amazing experience with Dr. Hayag! I went in for a preventative skin check and botox. She is incredibly thorough, knowledgeable, and precise. I can't wait for my next visit!
Rachel AncelTrustindex verifies that the original source of the review is Google.
Dr. Hayag has been my dermatologist since I was young, and I truly cannot recommend her highly enough. She treated my acne when I was younger, and I have continued to see her over the years for any skin concerns that come up. She is always incredibly thorough, knowledgeable, and caring, and I completely trust her. On top of that, her entire staff is so warm, kind, and lovely, which makes every visit such a positive experience. I’m so grateful to have had her as my dermatologist for so many years.
KatieTrustindex verifies that the original source of the review is Google.
Landy AguiarTrustindex verifies that the original source of the review is Google.
My entire family has been seeing Dr Hayag for over a decade for general dermatology. She’s extremely knowledgeable and provides the best level of care and advice. She’s been equally good for my kids as teens and young adults, focusing on prevention and healthy skin habits. The entire staff is kind and friendly, keeps appointments on time and has great communication. I’m a patient for life - a wonderful doctor and practice.
Patricia FalconiTrustindex verifies that the original source of the review is Google.
Dr. Hayag is an amazing doctor. Very caring and gentle with her patients. I have been with her for years and will continue to be with her. I highly recommend her.
Ann NellissenTrustindex verifies that the original source of the review is Google.
Everyone in the office is so kind and sweet to me I appreciate how they take their time to address my concerns
mimi chungTrustindex verifies that the original source of the review is Google.
My visit to Dr. Hayag’s Office was superb. No waiting, lovely professional help and Dr. Hayag with an easy confident manner, artistic eye and quick hands managed to make my experience the best ever. I’m so grateful to be in her care.
mary ConleyTrustindex verifies that the original source of the review is Google.
⭐️⭐️⭐️⭐️⭐️ Dr. Hayag is an extraordinary dermatologist whose expertise, compassion, and commitment to excellence are unmatched. I have been under her care for over 15 years, and she remains the only dermatologist I trust implicitly. I travel from out of state, over two hours each way for my appointments, which speaks volumes about the caliber of her care. Dr. Hayag’s mastery of dermatology is second to none. She stays at the forefront of innovation, continually advancing her practice by attending leading dermatology conferences and incorporating the most cutting-edge techniques and treatments. Yet what truly distinguishes her is not just her knowledge, but her humanity. She takes the time to listen, to educate, and to ensure her patients feel understood and empowered in every decision. Her genuine care and personal attention are evident in every interaction. She is meticulous, insightful, and wholly dedicated to achieving the best outcomes for her patients. Her office reflects her professionalism and taste, immaculate, serene, and inviting. Her staff embodies the same warmth and excellence she brings to her work, creating an environment that feels both luxurious and deeply personal. Dr. Hayag represents the gold standard in dermatology: exceptional skill, unwavering integrity, and a sincere devotion to her patients’ well-being. I highly and wholeheartedly recommend her to anyone seeking the very best in dermatologic care.
Mary Ann MTrustindex verifies that the original source of the review is Google.
My favorite mult-generational doctor! A long-time patient, I trust her judgment and skills so much that I've sent my daughters to Dr. Hayag too!
Bee-Ann Benson
Your Care Begins With A Conversation



Dr. Marie V. Hayag



Glassifier is a precise, peptide-based glass skin treatment, and your plan should fit your skin. At Fifth Avenue Aesthetics, Dr. Marie Hayag brings a physician-led approach to every Glassifier treatment. She looks closely at your concerns, whether that’s pigmentation, fine lines, or texture, and plans a course of sessions around your goals.
Rather than treating one concern in isolation, Dr. Hayag looks at your skin as a whole. That may mean Glassifier on its own, or as part of a broader plan that can include other treatments she offers, all aimed at natural-looking, balanced results.


“The right approach depends on your skin, not a standard protocol.”
Frequently Asked Questions
What is Glassifier?
Glassifier is a minimally invasive glass skin treatment powered by patented spicule technology. It precisely delivers GHK peptide into the skin to visibly improve fine lines, skin texture, and pigmentation, helping you achieve a glass-like radiance.
How long does a Glassifier treatment take?
A Glassifier session takes approximately 20 minutes. It is performed through a proprietary topical massage protocol.
How many Glassifier sessions will I need?
Glassifier is recommended as a course of 3–5 sessions spaced 2–4 weeks apart. Dr. Hayag will recommend the number of sessions based on your skin and goals.
Is there downtime after Glassifier?
Glassifier has minimal downtime. Dr. Hayag will walk you through aftercare so you know what to expect after each session.
What skin concerns does Glassifier treat?
Glassifier targets three main concerns: pigmentation (uneven skin tone, sunspots, and post-inflammatory hyperpigmentation), fine lines and wrinkles (including early wrinkles around the mouth and eyes), and skin texture (enlarged pores, rough or uneven skin, and dullness).
How does Glassifier work?
Glassifier uses patented spicule technology to deliver GHK peptide into the skin. ALTUM® Peptides reach the epidermal layer, where glutathione in the skin releases the peptide from its carrier. The released peptides stimulate fibroblasts, which stimulates collagen production and boosts skin regeneration.
Is Glassifier the same as microneedling?
No. Glassifier is its own treatment category, separate from microneedling and facials. It uses patented spicule technology and a proprietary topical massage protocol to deliver GHK peptide into the skin.
Can Glassifier be combined with other treatments Dr. Hayag offers?
Dr. Hayag can review your skin and any treatments you’re considering during your consultation, then let you know how Glassifier fits into your plan.
Experience Glassifier Peptide Skin Treatment in New York City
Schedule a personalized consultation with Marie Hayag, MD, and her experienced team to find out if Glassifier is right for you. Your plan starts with a close look at your concerns, from pigmentation to fine lines and texture, so each session works toward smoother, more radiant skin.

Give Us A Call
212.722.2055
